Mobile phone footage shows anti-government protests in the west Iranian city of Kermanshah.
Around 300 people gathered for what they described as a 'call by the anti-revolution'.
Large numbers also reportedly turned out in Rasht and smaller groups in Isfahan, Hamadan and the country's capital, Tehran.
The events come after hundreds rallied in Iran's second largest city of Mashhad on Thursday.
The protests are against rising prices, alleged corruption and the Islamic Republic's costly involvement in regional conflicts such as Syria and Iraq.
Missiles can be seen being thrown at Iranian police, who use water cannon to disperse the demonstrations.
The protests are the most serious and widespread expressions of public discontent in Iran since 2009.