Available from this summer in the US, the card will give users Bitcoin rewards on their purchases.
Mastercard Inc and US cryptocurrency exchange Gemini will launch the first credit card that gives users digital currency "rewards" on purchases this year, deepening the involvement of major payment firms in the emerging asset class.
Users of the card will from this summer receive up to 3 per cent in Bitcoin or other cryptocurrencies on their purchases, the companies said in a statement, with the digital currency deposited in the cardholder's Gemini account.
The card will be issued by WebBank, a Utah-based digital lender.
Payment giants from Mastercard and Visa Inc to PayPal Holdings Inc have stepped up their engagement with cryptocurrencies in recent months, as larger investors and companies warm to bitcoin and its kin.
Mastercard said in February it was planning to offer support for some cryptocurrencies on its network this year, while Visa will also allow the use of cryptocurrency to settle transactions on its payment network.
"As consumers go about spending in various acceptance locations, now they get a chance to earn reward in the form of crypto," Raj Dhamodharan, Mastercard's head of digital assets and blockchain products & partnerships, said.
The card will be available in the United States.