Former Bosnian Serb leader Radovan Karadzic has been found guilty of 10 of 11 charges by UN judges at the International Criminal Tribunal for the former Yugoslavia in the Hague.
The 70-year-old was found guilty of genocide for his involvement in the 1995 massacre in Srebrenica in which 8,000 Muslim men and boys were murdered in the space of a few days.
He was acquitted by the tribunal of a count of genocide in connection with the Bosnian municipalities.
UN judges also said that the former Bosnian Serb leader was criminally responsible for the siege of Sarajevo and crimes against humanity in other towns and villages during the Bosnian war of the 1990s.
The judges sentenced him to 40 years in prison but the length will be reduced as he has been in custody since 2008.
Karadzic, who is the most senior political figure to be convicted by the International Criminal Tribunal for the former Yugoslavia is to appeal the decision by the judges.