The 26-year-old will take a lead of one minute 46 seconds. Spain's Enric Mas and Colombia's Miguel Angel Lopez finished first and second to put themselves onto the general classification podium with one stage remaining
Spain's Enric Mas (Quick-Step Floors) and Colombia's Miguel Angel Lopez (Astana) finished first and second to put themselves onto the general classification podium with one stage remaining in the Vuelta a Espana.
Britain's Simon Yates all but assured himself victory by finishing third in Saturday's 20th and penultimate stage.
The 26-year-old Michelton-Scott rider survived an arduous final mountain stage to the Coll de la Gallina and will take a lead of one minute 46 seconds into Sunday's final processional stage to Madrid.
Sunday's 21st stage is a flat 101-kilometer ride from Alcorcon to the Spanish capital.