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Portrait of the Empress Catherine the Great by Dmitry Levitsky, with her letter to Count Piotr Aleksandrovich Rumiantsev on Vaccination Against Smallpox, 20 April 1787.

Video. How was Russia's Catherine the Great a vaccination trailblazer?

Updated:

In a 1787 letter, Catherine the Great describes step by step how to organise a vaccination campaign against smallpox in Russia. A portrait along with the letter are up for auction in December.

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