It means Italy are in danger of failing to qualify for the first time since 1958
Ireland are without two midfielders who will be needed to stop Danish playmaker Christian Eriksen.
Australia beat Syria 3-2 on aggregate, dashing their hopes of a 2018 World Cup spot.
The World Cup firsts, familiar faces and unlikely occurrences we can expect at Russia 2018
Tiny Iceland, population 330,000, has made sporting history by becoming the smallest nation ever to qualify for the football World Cup.
With 15 teams already certain for Russia 2018, the final round of qualifiers sees some big names facing elimination from football's top tournament.