It is an annual event on Washington's National Mall - an annual cry against abortion.
And this year, demonstrators in the March for Life on Friday were excited to hear from a president they see as an ally, for his policies on restricting abortion access.
On the eve of the first anniversary of his inauguration, Donald Trump became the first sitting president to address the event live by video link.
"Today, I am announcing that we have just issued a new proposal to protect consciences, rights and religious freedoms of doctors, nurses and other medical professionals," Trump told participants.
"We are protecting the sanctity of life and the family as the foundation of our society".
Rallies of a different kind are planned this weekend.
A year after millions of women demonstrated against Donald Trump, the second Women's March will be held in cities across the US and beyond.
Women's solidarity on issues like sexual harassment has spurred recent social media campaigns.