Olympiacos Piraeus thrashed Anadolu Efes Istanbul on Thursday to notch up their first win of the new campaign.
Georgios Printezis and Vassilis Spanoulis starred for the hosts who opened a 38-19 margin midway through the second quarter.
Efes tried their best to pull themselves back into the encounter but the Greeks were just too good on the day.
Olympiacos ran away with the tie in the fourth quarter to seal a 90-66 victory.
Spanoulis produced a stunning performance all night long at the Peace and Friendship Stadium. He ended with 17 points and nine assists and became only the second player in competition’s history to reach 3,000 career points.
Cedi Osman scored a career and game high 22 points in defeat for Istanbul.
Elsewhere, Brose Bamberg rallied from a 12-point second-half deficit on home court to beat Unics Kazan and also register their first win of the new season.
Unics led for the majority of the night thanks in part from impressive displays from Keith Langford and Coty Clarke.
But Janis Strelnieks, Nikos Zisis and Darius Miller clicked in the fourth and rallied the hosts with 17 consecutive points and eventually went ahead in the final minute.
The German outfit managed to hold off their opponents to prevail 89-86.
Strelnieks paced the winners with 17 points while Keith Langford led the way with 24 points for Kazan.
Bamberg next face Panathinaikos while Unics take on Darussafaka Dogus Istanbul.