Five people were killed on Thursday in another day of attacks in Israel and the West Bank.
A teenage American was reportedly one of three to die in a shooting and car ramming onslaught near the Gush Etzion settlement bloc in the West Bank.
According to police, a Palestinian man drove along the shoulder of the main road and shot at crawling traffic.
Police say he was seized when his car stopped after hitting another vehicle.
Apart from the American, who was an 18-year-old tourist according to Fox News, the two other victims were identified as an Israeli and another Palestinian.
At least seven other people were wounded, a medical source said.
Earlier, two people were stabbed to death by a Palestinian at a commercial building in Tel Aviv.
Police said the assailant knifed worshippers gathered for afternoon prayers in a shop selling Jewish religious items.
“A Palestinian terrorist stabbed two Israeli men who were injured critically and taken to hospital.
“What we confirm until now is that two Israelis have been murdered in that terrorist attack,” said Israeli police spokesman Micky Rozenfeld.
“The suspect was captured and is being questioned at the moment.”
It brings to 18 the number of Israelis and others who have died, along with 80 Palestinians, in a wave of violence over the past seven weeks.
Police say that more than half of the Palestinians killed in recent weeks died at the scene of attacks on Israelis and that most of the rest died in violent protests in the West Bank and near the Gaza border.
Palestinian allegations that Israel was trying to alter the religious status quo at a Jerusalem holy site, known to Muslims as the Noble Sanctuary, where the al-Aqsa mosque stands, and to Jews as Temple Mount, have partly fuelled the violence.
Non-Muslim prayer is banned around al-Aqsa and Israel has said it will not change that.
But more visits in recent years by Jewish religious activists and ultra-nationalist Israeli politicians to the complex, where two biblical temples once stood, have done little to convince the Palestinians.
Earlier on Thursday, three 15-year-old Palestinian girls attempted to infiltrate an Israeli military post in the West Bank, the military said.
Soldiers apprehended them, and the military said three knives were found in their possession.