The fire broke out in Novi Sad, some 90 kilometres north of Belgrade.
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A house fire in a northern Serbian city early Friday killed six people, including four children, police said.
The fire erupted around 3 am in Novi Sad, some 90 kilometres north of the capital Belgrade, Serbian Interior Minister Ivica Dacic said.
An emergency doctor told state television channel RTS that all the victims were already dead when the medical team reached the scene.
Dacic said in a statement that initial findings suggest the cause could have been a charging electric scooter.
The children were between two and seven years old, Dacic said. Police are working to establish the victims' identity but they assume they are all members of a family registered at the address, he added.
Serbian media published photos from the scene showing charred items in a small brick house, including a baby stroller and a washing machine.