Wales carried their good form from the European Championships into the World Cup qualifiers.
Goals by Sam Vokes, Joe Allen and a Gareth Bale brace earned the Euro 2016 semifinalists a 4-0 win over Moldova.
Wales now top Group D.
Italy bounced back from their 3-1 friendly defeat against France with victory against Israel.
Goals by Graziano Pelle, Antonio Candreva and Ciro Immobile gave the Azurri a 3-1 win. Tal Ben Chaim scored a consolation for the home side.
Ivan Rakitic’s 44th minute goal was cancelled out by
Hakan Calhanoglu as Croatia and Turkey played out a 1-1 draw at Croatia’s Stadion Maksimir.
The draw leaves Croatia second in Group I.
Two goals each from David Silva, Diego Costa, Alvaro Morata saw Spain thump Liechenstein 8-0 in their World Cup opener in Julen Lopetegui’s first game as manager.