(Reuters) - London's FTSE 100 was led lower on Thursday by spirits-maker Diageo and clothing chain Next, while traders awaited the Bank of England's policy decision after its U.S. counterpart lowered interest rates but was guarded on future cuts.
The blue-chip bourse <.FTSE> edged 0.2% lower by 0707 GMT - its fourth straight day in the red, while the more domestically-focused FTSE 250 index <.FTMC> dipped 0.1% ahead of BoE's interest rate decision.
Next <NXT.L> skidded 5% after it flagged that the first few weeks of the Autumn season were disappointing and Diageo <DGE.L> slipped 1.4% after it said it was "not immune" to changes in global trade policies as it laid out targets for the year.
Midcap constituent IG Group <IGG.L> jumped 6% as it said client numbers grew thanks to favourable market conditions in August, while small cap Kier Group <KIE.L> lost 7% after the contractor posted an annual loss.
(Reporting by Muvija M in Bengaluru; Editing by Angus MacSwan)
