The Syrian army is said to have stormed into the city of Baniyas, targeting districts where people have been defying President Assad’s rule.
According to one human rights campaigner, three women were shot dead as they demonstrated near the coastal city.
It is one of several towns to have seen an uprising in recent weeks.
The bloodiest confrontations in Friday’s “day of defiance” came in Homs, where the violence brought claim and counter-claim from protesters and the authorities.
Concern is now focussed on Baniyas, where most communication has been cut.
A human rights campaigner said he had managed to contact residents who reported heavy gunfire and search operations being carried out by security forces.
Hama also saw trouble on Friday. The repression here and elsewhere may not be on the scale it was in 1982, when 20 or 30 thousand were killed in a security crackdown.
But there are signs it is doing enough to keep the regime in power.
Hundreds have been killed. An opposition facebook message calls for elections but admits that not enough protesters have been mobilised to bring about revolution.
“The flame has died a little,” it says.