It is one of the largest collections of ancient Chinese art in the world.
The National Palace Museum in Taiwan is home to some 700,000 such artifacts.
But many are considered national treasures by both Beijing and Taipei.
China has claimed sovereignty over Taiwan since the end of the Chinese civil war.
The museum has long feared that Chinese officials would seize the items.
So much so that it has rarely loaned them abroad.
Last month, however, an agreement was signed with Japan.
It came two years after the Japanese government passed a law forbidding such seizures.
Until now the only overseas exhibitions have been held in the US, France, Germany and Austria.
The Japanese exhibition opens in Tokyo and Kyushu in June.