The Taliban says it was behind a suicide attack near the heavily guarded NATO headquarters in the Afghan capital, Kabul, as the country marks a national holiday.
At least six people were killed by the blast near the entrance of Camp Eggers, a sprawling base that is home to some 2,500 coalition staff.
Young children are said to be among the dead, according to officials.
The insurgents say they were targeting America’s CIA offices they claim are used for recruiting Afghans for spying.
In Tirin Kot, the capital of Uruzgan province, two tribal elders were killed when a device went off outside one of their homes.
A roadside bomb in the Nahri Sarraj district of neighbouring Helmand province killed two women and injured two others.
The attacks coincides with commemorations by supporters of an iconic anti-Taliban commander who was murdered on 9 September, 2001. Ahmad Shah Massoud was killed in a suicide bombing by al-Qaeda activists posing as journalists.